PCA3 NONCODING RNA IS INVOLVED IN THE CONTROL OF PROSTATE-CANCER CELL SURVIVAL AND MODULATES ANDROGEN RECEPTOR SIGNALING

PCA3 noncoding RNA is involved in the control of prostate-cancer cell survival and modulates androgen receptor signaling

Abstract Background PCA3 is a non-coding RNA (ncRNA) that is highly expressed in prostate cancer (PCa) cells, but its functional role is unknown.To investigate its putative function in PCa biology, we used gene expression knockdown by small interference RNA, and also analyzed its involvement in androgen receptor (AR) signaling.Methods LNCaP and PC3

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Comparison of different sequential assimilation algorithms for satellite-derived leaf area index using the Data Assimilation Research Testbed (version Lanai)

The leaf area index (LAI) is a crucial parameter for understanding the exchanges of mass and energy between terrestrial ecosystems and the atmosphere.In this study, the Data Assimilation Research Testbed (DART) has been successfully coupled to the Community Land Model with explicit carbon and nitrogen components (CLM4CN) by assimilating Global Land

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First trimester prenatal metal mixtures, vitamins, and hypertensive disorders of pregnancy in the project viva cohort

Background: Hypertensive disorders of pregnancy (HDP) such as preeclampsia and gestational hypertension are major contributors to maternal and child morbidity and mortality.Previous studies have reported associations with selected metals and vitamins but are limited in sample size and bismarck armb?nd non-prospective study designs.We evaluated pros

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Neuter gender in the languages of Aru

This paper examines gender agreement summer beauty ornamental onion in three little-known languages of the Aru Islands and places them within the larger pattern of "neuter gender" in eastern Indonesia.For each language, I look first at the variety of agreement targets that are controlled by gendered nouns.Secondly, I look at the semantics of nouns

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